Clinical and genomic models are both used to predict breast cancer outcomes, but they are often combined using simple linear rules that do not account for how their risk scores relate, especially at the extremes. Using the METABRIC breast cancer cohort, we studied whether directly modeling the joint relationship between clinical and genomic machine learning risk scores could improve risk stratification for 5-year cancer-specific mortality. We created a binary 5-year cancer-death outcome and defined two sets of predictors: a clinical set (demographic, tumor, and treatment variables) and a genomic set (gene-expression $z$-scores). We trained several supervised classifiers, such as Random Forest and XGBoost, and used 5-fold cross-validated predicted probabilities as unbiased risk scores. These scores were converted to pseudo-observations on $(0,1)^2$ to fit Gaussian, Clayton, and Gumbel copulas. Clinical models showed good discrimination (AUC 0.783), while genomic models had moderate performance (AUC 0.681). The joint distribution was best captured by a Gaussian copula (bootstrap $p=0.997$), which suggests a symmetric, moderately strong positive relationship. When we grouped patients based on this relationship, Kaplan-Meier curves showed clear differences: patients who were high-risk in both clinical and genomic scores had much poorer survival than those high-risk in only one set. These results show that copula-based fusion works in real-world cohorts and that considering dependencies between scores can better identify patient subgroups with the worst prognosis.

Fine-tuning BERT for text classification can be computationally challenging and requires careful hyper-parameter tuning. Recent studies have highlighted the potential of quantum algorithms to outperform conventional methods in machine learning and text classification tasks. In this work, we propose a hybrid approach that integrates an n-qubit quantum circuit with a classical BERT model for text classification. We evaluate the performance of the fine-tuned classical-quantum BERT and demonstrate its feasibility as well as its potential in advancing this research area. Our experimental results show that the proposed hybrid model achieves performance that is competitive with, and in some cases better than, the classical baselines on standard benchmark datasets. Furthermore, our approach demonstrates the adaptability of classical-quantum models for fine-tuning pre-trained models across diverse datasets. Overall, the hybrid model highlights the promise of quantum computing in achieving improved performance for text classification tasks.

The rapid growth of edge devices has driven the demand for deploying artificial intelligence (AI) at the edge, giving rise to Tiny Machine Learning (TinyML) and its evolving counterpart, Tiny Deep Learning (TinyDL). While TinyML initially focused on enabling simple inference tasks on microcontrollers, the emergence of TinyDL marks a paradigm shift toward deploying deep learning models on severely resource-constrained hardware. This survey presents a comprehensive overview of the transition from TinyML to TinyDL, encompassing architectural innovations, hardware platforms, model optimization techniques, and software toolchains. We analyze state-of-the-art methods in quantization, pruning, and neural architecture search (NAS), and examine hardware trends from MCUs to dedicated neural accelerators. Furthermore, we categorize software deployment frameworks, compilers, and AutoML tools enabling practical on-device learning. Applications across domains such as computer vision, audio recognition, healthcare, and industrial monitoring are reviewed to illustrate the real-world impact of TinyDL. Finally, we identify emerging directions including neuromorphic computing, federated TinyDL, edge-native foundation models, and domain-specific co-design approaches. This survey aims to serve as a foundational resource for researchers and practitioners, offering a holistic view of the ecosystem and laying the groundwork for future advancements in edge AI.

Abstract--Recent advancements in large artificial intelligence models (LAMs) are driving significant innovations in mobile edge computing within next-generation wireless networks. However, the substantial demands for computational resources and large-scale training data required to train LAMs conflict with the limited storage and computational capacity of edge devices, posing significant challenges to training and deploying LAMs at the edge. In this work, we introduce the Networked Mixture-of-Experts (NMoE) system, in which clients infer collaboratively by distributing tasks to suitable neighbors based on their expertise and aggregate the returned results. For training the NMoE, we propose a federated learning framework that integrates both supervised and self-supervised learning to balance per-sonalization and generalization, while preserving communication efficiency and data privacy. We conduct extensive experiments to demonstrate the efficacy of the proposed NMoE system, providing insights and benchmarks for the NMoE training algorithms. The recent wave of progress in large artificial intelligence models (LAMs) has triggered a variety of novel technologies, such as large language models (LLMs), vision-language models (VLMs), and artificial intelligence (AI) agents [1], which present exciting opportunities for next-generation wireless communications.

This paper presents an integrated robotic fused deposition modeling additive manufacturing system featuring closed-loop thermal control and intelligent in-situ defect correction using a 6-degree of freedom robotic arm and an Oak-D camera. The robot arm end effector was modified to mount an E3D hotend thermally regulated by an IoT microcontroller, enabling precise temperature control through real-time feedback. Filament extrusion system was synchronized with robotic motion, coordinated via ROS2, ensuring consistent deposition along complex trajectories. A vision system based on OpenCV detects layer-wise defects position, commanding autonomous re-extrusion at identified sites. Experimental validation demonstrated successful defect mitigation in printing operations. The integrated system effectively addresses challenges real-time quality assurance. Inverse kinematics were used for motion planning, while homography transformations corrected camera perspectives for accurate defect localization. The intelligent system successfully mitigated surface anomalies without interrupting the print process. By combining real-time thermal regulation, motion control, and intelligent defect detection & correction, this architecture establishes a scalable and adaptive robotic additive manufacturing framework suitable for aerospace, biomedical, and industrial applications.

Kernel Stein discrepancies (KSDs) have become a principal tool for goodness-of-fit testing, but standard KSDs are often insensitive to higher-order dependency structures, such as tail dependence, which are critical in many scientific and financial domains. We address this gap by introducing the Copula-Stein Discrepancy (CSD), a novel class of discrepancies tailored to the geometry of statistical dependence. By defining a Stein operator directly on the copula density, CSD leverages the generative structure of dependence, rather than relying on the joint density's score function. For the broad class of Archimedean copulas, this approach yields a closed-form Stein kernel derived from the scalar generator function. We provide a comprehensive theoretical analysis, proving that CSD (i) metrizes weak convergence of copula distributions, ensuring it detects any mismatch in dependence; (ii) has an empirical estimator that converges at the minimax optimal rate of $O_P(n^{-1/2})$; and (iii) is provably sensitive to differences in tail dependence coefficients. The framework is extended to general non-Archimedean copulas, including elliptical and vine copulas. Computationally, the exact CSD kernel evaluation scales linearly in dimension, while a novel random feature approximation reduces the $n$-dependence from quadratic $O(n^2)$ to near-linear $\tilde{O}(n)$, making CSD a practical and theoretically principled tool for dependence-aware inference.

Abstract-- Medical decision systems increasingly rely on data from multiple sources to ensure reliable and unbiased diagnosis. However, existing multimodal learning models fail to achieve this goal because they often ignore two critical challenges. First, various data modalities may learn unevenly, thereby converging to a model biased towards certain modalities. Second, the model may emphasize learning on certain demographic groups causing unfair performances. The two aspects can influence each other, as different data modalities may favor respective groups during optimization, leading to both imbalanced and unfair multimodal learning. This paper proposes a novel approach called MultiFair for multimodal medical classification, which addresses these challenges with a dual-level gradient modulation process. We conduct extensive experiments on two multimodal medical datasets with different demographic groups. The results show that MultiFair outperforms state-of-the-art multimodal learning and fairness learning methods.

Abstract--Vision language models (VLMs), such as CLIP and OpenCLIP, can encode and reflect stereotypical associations between medical professions and demographic attributes learned from web-scale data. We present an evaluation protocol for healthcare settings that quantifies associated biases and assesses their operational risk. Our methodology (i) defines a taxonomy spanning clinicians and allied healthcare roles (e.g., surgeon, cardiologist, dentist, nurse, pharmacist, technician), (ii) curates a profession-aware prompt suite to probe model behavior, and (iii) benchmarks demographic skew against a balanced face corpus. Empirically, we observe consistent demographic biases across multiple roles and vision models. Our work highlights the importance of bias identification in critical domains such as healthcare as AI-enabled hiring and workforce analytics can have downstream implications for equity, compliance, and patient trust. Vision language models (VLMs) constitute a class of AI architectures that learn joint representation by aligning visual perception with natural language semantics [1]. Typically, an image encoder is paired with a text encoder and trained to inhabit a shared embedding space that supports cross-modal correspondence between images and linguistic descriptions. One such instance is OpenAI's CLIP (Contrastive Language Image Pretraining) which is optimized on roughly 400 million image-text pairs and exhibits strong zero-shot ability for The code can be found at https://github.com/zohaibhasan066/ VLMs enable a broad spectrum of multimodal functionalities, including image captioning, visual question answering, and bidirectional text-image retrieval with downstream applications in search, recommendation, and human-computer interaction.

Recent advances in distributed swarm learning (DSL) offer a promising paradigm for edge Internet of Things. Such advancements enhance data privacy, communication efficiency, energy saving, and model scalability. However, the presence of non-independent and identically distributed (non-i.i.d.) data pose a significant challenge for multi-access edge computing, degrading learning performance and diverging training behavior of vanilla DSL. Further, there still lacks theoretical guidance on how data heterogeneity affects model training accuracy, which requires thorough investigation. To fill the gap, this paper first study the data heterogeneity by measuring the impact of non-i.i.d. datasets under the DSL framework. This then motivates a new multi-worker selection design for DSL, termed M-DSL algorithm, which works effectively with distributed heterogeneous data. A new non-i.i.d. degree metric is introduced and defined in this work to formulate the statistical difference among local datasets, which builds a connection between the measure of data heterogeneity and the evaluation of DSL performance. In this way, our M-DSL guides effective selection of multiple works who make prominent contributions for global model updates. We also provide theoretical analysis on the convergence behavior of our M-DSL, followed by extensive experiments on different heterogeneous datasets and non-i.i.d. data settings. Numerical results verify performance improvement and network intelligence enhancement provided by our M-DSL beyond the benchmarks.

-- Fairness remains a critical concern in healthcare, where unequal access to services and treatment outcomes can adversely affect patient health. While Federated Learning (FL) presents a collaborative and privacy-preserving approach to model training, ensuring fairness is challenging due to heterogeneous data across institutions, and current research primarily addresses non-medical applications. To fill this gap, we establish the first experimental benchmark for fairness in medical FL, evaluating six representative FL methods across diverse demographic attributes and imaging modalities. We introduce FairFedMed, the first medical FL dataset specifically designed to study group fairness (i.e., demographics). It comprises two parts: FairFedMed-Oph, featuring 2D fundus and 3D OCT ophthalmology samples with six demographic attributes; and FairFedMed-Chest, which simulates real cross-institutional FL using subsets of CheXpert and MIMIC-CXR. Together, they support both simulated and real-world FL across diverse medical modalities and demographic groups. Existing FL models often underperform on medical images and overlook fairness across demographic groups. To address this, we propose FairLoRA, a fairness-aware FL framework based on SVD-based low-rank approximation. Experimental results on the FairFedMed dataset demonstrate that FairLoRA not only achieves state-of-the-art performance in medical image classification but also significantly improves fairness across diverse populations. Our code and dataset can be accessible via the link: https: //wang.hms.harvard.edu/fairfedmed/. Minghan Li, Y an Luo, and Mengyu Wang are with Harvard AI and Robotics Lab and Harvard Ophthalmology AI lab, Harvard University, Boston, Massachusetts, USA (e-mail: mili4@meei.harvard.edu;